ANZSBT and Australian Red Cross Lifeblood presents the following webinar.
Prevention of transfusion associated graft versus host disease – 2024 update
22nd May 2024 13:00-14:00 AEST
Transfusion associated graft versus host disease (TA-GVHD) is a rare, devastating and usually fatal complication following transfusion of cellular blood components caused by engraftment of donor derived T cells into transfusion recipients. Irradiation of blood components for patients at risk has been the standard of care for TA-GVHD prevention, yet we know may be overlooked in complex health care systems, and leaves a small residual risk in patients not in traditional risk groups. Irradiation also damages red cells, limiting storage duration, particularly for patients at risk of hyperkalaemia. This limits the ability to manage residual risk. At the same time, emerging evidence has suggested some protective effect of leukocyte depletion and a reduced risk with longer cold storage times. This webinar will summarise the causes, risk factors and protective factors for TA-GVHD and describe risk mitigation approaches as outlined in the 2024 revision of ANZSBT TA-GVHD prevention Guidelines.
Presenters:
Dr Philip Crispin. Vice President and Clinical Transfusion Practice Committee member, ANZSBT
Dr Bryony Ross, Chair, Clinical Transfusion Practice Committee, ANZSBT
Ms Kristen Brown, Clinical Transfusion Practice Committee, ANZSBT
Ms Helen Stathopoulos, Transfusion Science Standing Committee, ANZSBT
Register here: Prevention of transfusion associated graft versus host disease – 2024 update